I am a physician-scientist who organizes a research group at UCSF focused on tissue immunology. We are particularly excited to understand stromal tissue niches for diverse lymphocyte subsets, including how these regional immune hubs change over lifespan and in disease. Using 3D quantitative imaging approaches, we have helped characterize sterile 'boundary' niches in multiple tissues, defined by adventitial fibroblasts that can support type 2 lymphocytes. We seek to understand how niche fibroblasts respond to immune signals and remodel these homes in chronic inflammatory settings. Our work spans multiple organs and disease states, with a current focus on lung, liver, skin and brain. In addition to research, I engage in limited clinical work as a hematopathologist and am passionate about education of our trainees, including organizing and teaching the first year medical student immunology course.